{"id":405,"date":"2022-06-25T12:10:55","date_gmt":"2022-06-25T12:10:55","guid":{"rendered":"https:\/\/bionanotec.eu\/?page_id=405"},"modified":"2023-04-25T15:46:21","modified_gmt":"2023-04-25T15:46:21","slug":"3d-nanobiosamples","status":"publish","type":"page","link":"https:\/\/bionanotec.eu\/index.php\/3d-nanobiosamples\/","title":{"rendered":"3D NANOBIOSAMPLES"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"405\" class=\"elementor elementor-405\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-1e237e8 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"1e237e8\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-d491c4c\" data-id=\"d491c4c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-40cdf91 elementor-widget elementor-widget-heading\" data-id=\"40cdf91\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">3D NANOBIOSAMPLES  \/CONCEPT\/0521\/0069<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-2af9716 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"2af9716\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-1fccc87\" data-id=\"1fccc87\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-81f5d61 elementor-widget elementor-widget-image\" data-id=\"81f5d61\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"171\" src=\"https:\/\/bionanotec.eu\/wp-content\/uploads\/2023\/04\/\u0395\u03a4\u03a0\u0391-\u0394\u03b9\u03b1\u03c1\u03b8\u03c1\u03c9\u03c4\u03b9\u03ba\u03ac-2021-2027-EN-1024x171.png\" class=\"attachment-large size-large wp-image-687\" alt=\"\" srcset=\"https:\/\/bionanotec.eu\/wp-content\/uploads\/2023\/04\/\u0395\u03a4\u03a0\u0391-\u0394\u03b9\u03b1\u03c1\u03b8\u03c1\u03c9\u03c4\u03b9\u03ba\u03ac-2021-2027-EN-1024x171.png 1024w, https:\/\/bionanotec.eu\/wp-content\/uploads\/2023\/04\/\u0395\u03a4\u03a0\u0391-\u0394\u03b9\u03b1\u03c1\u03b8\u03c1\u03c9\u03c4\u03b9\u03ba\u03ac-2021-2027-EN-300x50.png 300w, https:\/\/bionanotec.eu\/wp-content\/uploads\/2023\/04\/\u0395\u03a4\u03a0\u0391-\u0394\u03b9\u03b1\u03c1\u03b8\u03c1\u03c9\u03c4\u03b9\u03ba\u03ac-2021-2027-EN-768x128.png 768w, https:\/\/bionanotec.eu\/wp-content\/uploads\/2023\/04\/\u0395\u03a4\u03a0\u0391-\u0394\u03b9\u03b1\u03c1\u03b8\u03c1\u03c9\u03c4\u03b9\u03ba\u03ac-2021-2027-EN.png 1500w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-8ec401f elementor-widget elementor-widget-video\" data-id=\"8ec401f\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;video_type&quot;:&quot;hosted&quot;,&quot;autoplay&quot;:&quot;yes&quot;,&quot;controls&quot;:&quot;yes&quot;}\" data-widget_type=\"video.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"e-hosted-video elementor-wrapper elementor-open-inline\">\n\t\t\t\t\t<video class=\"elementor-video\" src=\"https:\/\/bionanotec.eu\/wp-content\/uploads\/2023\/03\/3D_NanoBiosamples_Concept.mp4\" autoplay=\"\" controls=\"\" controlsList=\"nodownload\"><\/video>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3d23827 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"3d23827\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-90613fb\" data-id=\"90613fb\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-85cfd65 elementor-widget elementor-widget-heading\" data-id=\"85cfd65\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">3D Characterisation Of The Nanomechanical Properties Of Biological Samples<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-cfa073f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"cfa073f\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-de596e3\" data-id=\"de596e3\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-56c9048 elementor-widget elementor-widget-text-editor\" data-id=\"56c9048\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default elementor-inline-editing pen\" contenteditable=\"true\" data-elementor-setting-key=\"title\" data-pen-placeholder=\"Type Here...\"><b>Funding body:<\/b> Cyprus Research and Innovation Foundation\u200b\u200b<\/h4>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-e20bb05\" data-id=\"e20bb05\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-22bd882 elementor-widget elementor-widget-image\" data-id=\"22bd882\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"198\" height=\"91\" src=\"https:\/\/bionanotec.eu\/wp-content\/uploads\/2022\/06\/rif_logo_EN-e1656162343926.png\" class=\"attachment-large size-large wp-image-485\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-96f5c3e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"96f5c3e\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-9f50d43\" data-id=\"9f50d43\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-adb419d elementor-widget elementor-widget-text-editor\" data-id=\"adb419d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default elementor-inline-editing pen\" contenteditable=\"true\" data-elementor-setting-key=\"title\" data-pen-placeholder=\"Type Here...\"><b>Funding Scheme:<\/b> Restart Research 2016-2020<\/h4>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-3e563d6\" data-id=\"3e563d6\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-104cf0a elementor-widget elementor-widget-image\" data-id=\"104cf0a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"311\" height=\"155\" src=\"https:\/\/bionanotec.eu\/wp-content\/uploads\/2022\/06\/restart_research_2016-2020.png\" class=\"attachment-large size-large wp-image-486\" alt=\"\" srcset=\"https:\/\/bionanotec.eu\/wp-content\/uploads\/2022\/06\/restart_research_2016-2020.png 311w, https:\/\/bionanotec.eu\/wp-content\/uploads\/2022\/06\/restart_research_2016-2020-300x150.png 300w\" sizes=\"(max-width: 311px) 100vw, 311px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-fc86ab2 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"fc86ab2\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-155d6c8\" data-id=\"155d6c8\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1016031 elementor-widget elementor-widget-text-editor\" data-id=\"1016031\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default elementor-inline-editing pen\" contenteditable=\"true\" data-elementor-setting-key=\"title\" data-pen-placeholder=\"Type Here...\"><strong>Programme:<\/strong> Proof of Concept for Technology \/ Knowhow Applications<\/h4>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2437131 elementor-widget elementor-widget-text-editor\" data-id=\"2437131\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default elementor-inline-editing pen\" contenteditable=\"true\" data-elementor-setting-key=\"title\" data-pen-placeholder=\"Type Here...\"><b>Funding Scheme:<\/b> Restart Research 2016-2020<\/h4>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b833d11 elementor-widget elementor-widget-text-editor\" data-id=\"b833d11\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default elementor-inline-editing pen\" contenteditable=\"true\" data-elementor-setting-key=\"title\" data-pen-placeholder=\"Type Here...\"><strong>Project Title:<\/strong> 3D CHARACTERISATION OF THE NANOMECHANICAL PROPERTIES OF BIOLOGICALSAMPLES<\/h4>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8476165 elementor-widget elementor-widget-text-editor\" data-id=\"8476165\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h4><strong>Acronym:<\/strong> 3D NANOBIOSAMPLES<\/h4>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-afc87eb elementor-widget elementor-widget-text-editor\" data-id=\"afc87eb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h4><strong>Duration:\u00a0 <\/strong>16\/5\/22-15\/2\/23<\/h4>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2e99a89 elementor-widget elementor-widget-text-editor\" data-id=\"2e99a89\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h4><strong>Budget:<\/strong>\u00a0 39.817, 92<b>\u20ac<\/b><\/h4>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9b9f225 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9b9f225\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-0ce174f\" data-id=\"0ce174f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-82ca6b8 elementor-widget elementor-widget-text-editor\" data-id=\"82ca6b8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h4><strong>Partners:<\/strong><\/h4>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-d184c79 elementor-section-content-middle elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"d184c79\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-3ca9984\" data-id=\"3ca9984\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-06846e0 elementor-widget elementor-widget-text-editor\" data-id=\"06846e0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h4>BioNanoTec LTD (Host Organization)<\/h4>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-15c58c2\" data-id=\"15c58c2\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d0ad1b2 elementor-widget elementor-widget-image\" data-id=\"d0ad1b2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"305\" height=\"76\" src=\"https:\/\/bionanotec.eu\/wp-content\/uploads\/2021\/07\/bionanotec_75-288x72.jpg\" class=\"attachment-large size-large wp-image-69\" alt=\"\" srcset=\"https:\/\/bionanotec.eu\/wp-content\/uploads\/2021\/07\/bionanotec_75.jpg 305w, https:\/\/bionanotec.eu\/wp-content\/uploads\/2021\/07\/bionanotec_75-300x75.jpg 300w, https:\/\/bionanotec.eu\/wp-content\/uploads\/2021\/07\/bionanotec_75-288x72.jpg 288w\" sizes=\"(max-width: 305px) 100vw, 305px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-3f77b2c elementor-section-content-middle elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"3f77b2c\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-5d5d8e6\" data-id=\"5d5d8e6\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-62ec49a elementor-widget elementor-widget-text-editor\" data-id=\"62ec49a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h4>EUC Research Centre<\/h4>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-f4289af\" data-id=\"f4289af\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-898fa25 elementor-widget elementor-widget-image\" data-id=\"898fa25\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"491\" height=\"118\" src=\"https:\/\/bionanotec.eu\/wp-content\/uploads\/2022\/06\/euc_logopng.png\" class=\"attachment-large size-large wp-image-521\" alt=\"\" srcset=\"https:\/\/bionanotec.eu\/wp-content\/uploads\/2022\/06\/euc_logopng.png 491w, https:\/\/bionanotec.eu\/wp-content\/uploads\/2022\/06\/euc_logopng-300x72.png 300w\" sizes=\"(max-width: 491px) 100vw, 491px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-fde17a5 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"fde17a5\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-f8cec72\" data-id=\"f8cec72\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2e29787 elementor-widget elementor-widget-heading\" data-id=\"2e29787\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">General Objectives of the project<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1100557 elementor-widget elementor-widget-text-editor\" data-id=\"1100557\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div id=\"pageContainer2\" class=\"_page_ysiwt_100 \" data-index=\"1\">Determining the mechanical properties of biological samples using Atomic Force Microscopy (AFM) has opened new possibilities for the characterization of biological materials and relative applications [1].The AFM indentation is the most extensively used method for the nanomechanical characterization of biological samples at the nanoscale; it can be equally applied from the characterization of single molecules and proteins to the characterization of complex biological samples such as cells and tissues [1]. However, the biological materials\u2019 characterization using AFM is still considered as a challenging procedure; many errors may arise mostly related to data processing and the misuse of contact mechanics models that consider the sample as an elastic half space (biological samples at the nanoscale are highly heterogeneous and non-isotropic materials) [1-2].Nevertheless, a new contact mechanics theory was recently developed; the average Young\u2019s modulus theory by members of the research team[2]. The aforementioned theory may be used for a complete mechanical characterization of any single region at the nanoscale; thus, it can reveal the depth-dependent mechanical properties of biological samples.The basic goal of this project is to use the average Young\u2019s modulus theory for a 3-dimensional (3D) mechanical characterization of biological samples at the nanoscale.It is significant to note that the mechanical properties of biological samples vary significantly as the indentation depth increases[2]; as a result,currently existing methods do not take this into account and their results depend on the respective AFM user selecting the maximum indentation depth.In other words, existing AFM methods provide a 2D characterization (since they do not take into account the mechanical properties\u2019 alterations in the 3rddimension, i.e., as the indentation depth increases and their results are user dependent.On the contrary, the proposed project aims towards the development of a software package (based on the average Young\u2019s modulus theory)able to derive3D mechanical patterns of any biological sample. The 3D characterization will be also applied on normal and cancer cells as a test of the software performance.The aforementioned samples are of out most scientific interest related to early cancer diagnosis[3] and other applications [4].A software package based on the average Young\u2019s modulus theory will be developed in order to correctly process the force curves(force\u2013indentation AFM data)of highly heterogeneous materials(e.g. cells). The software will be able to derive the average Young\u2019s modulus at different nano regions and for different indentation depths. As a result using multiple average Young\u2019s modulus values at different location on the xyz dimensional space will lead to a 3D mechanical characterization. To test the validity of the software experiments on reference samples (agarose gels) will be performed first. Subsequently, normal and cancerous cells from mice will be tested in order to derive accurate mechanical 3D mechanical patterns in each case. Thus, the basic limitation of AFM techniques which is the ability to acquire only 2-dimensionalinformationregarding the sample\u2019s mechanical properties will be overcome. Special attention will be also given to avoid increasing the complexity of the standard AFM experimental procedures.<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-b84704c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"b84704c\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5ccdb3d\" data-id=\"5ccdb3d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6958793 elementor-widget elementor-widget-heading\" data-id=\"6958793\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Scientific publications during the project<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9732692 elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"9732692\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-scroll\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">\u039aontomaris, S.V.; Stylianou, A.; Chliveros, G.; Malamou, A. AFM Indentation on Highly Heterogeneous Materials Using Different Indenter Geometries. Appl. Mech. 2023, 4, 460-475.<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-scroll\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Kontomaris, S.V., Stylianou, A., Malamou, A., Georgakopoulos, A., 2023, Is it mathematically correct to fit AFM data (obtained on biological materials) to equations arising from Hertzian mechanics?, Micron, Volume 164, 103384. DOI: 10.1016\/j.micron.2022.103384<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-scroll\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Kontomaris S V, Stylianou A, Chliveros G, Malamou A. Determining Spatial Variability of Elastic Properties for Biological Samples Using AFM. Micromachines 2023, 14, 182. DOI: 10.3390\/mi14010182\u200b<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-scroll\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Stylianos Vasileios Kontomaris, Andreas Stylianou, Anastasios Georgakopoulos and Anna Malamou, 2023, 3D AFM Nanomechanical Characterization of Biological Materials, Nanomaterials, Volume 13, Issue 3, 395. <span data-elementor-setting-key=\"icon_list.3.text\" data-pen-placeholder=\"Type Here...\">DOI:&nbsp;1<\/span>0.3390\/nano13030395<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-scroll\"><\/i>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Kontomaris S V, Malamou A. The truncated cone effect in AFM nanoindentation on soft samples. Micro and Nanosystems (pre-proof) DOI: 10.2174\/1876402915666230209140024\u200b<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-c1e7329 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"c1e7329\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-c7c571c\" data-id=\"c7c571c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8fff2a2 elementor-widget elementor-widget-heading\" data-id=\"8fff2a2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">References<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-befd574 elementor-widget elementor-widget-text-editor\" data-id=\"befd574\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>[1] Krieg M, Fl\u00e4schner G, Alsteens D et al. 2018 Atomic force microscopy-based mechanobiology. Nat. Rev. Phys., 1, 41-47.<\/p><p>[2] <strong>Kontomaris, S.V<\/strong>., Georgakopoulos, A., Malamou, A., Stylianou, A. 2021 The average Young&#8217;s modulus as a physical quantity for describing the depth-dependent mechanical properties of cells Mechanics of Materials,\u00a0 158, 103846.<\/p><p>[3] Stylianou A, Lekka, M, Stylianopoulos A 2018 AFM assessing of nanomechanical fingerprints for cancer early diagnosis and classification: from single cell to tissue level. Nanoscale 10 (45), 20930-20945.<\/p><p>[4] Wu P H, Aroush D RB, Asnacios A. et al. 2018 A comparison of methods to assess cell mechanical properties. Nat Methods 15, 491\u2013498.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>3D NANOBIOSAMPLES \/CONCEPT\/0521\/0069 https:\/\/bionanotec.eu\/wp-content\/uploads\/2023\/03\/3D_NanoBiosamples_Concept.mp4 3D Characterisation Of The Nanomechanical Properties Of Biological Samples Funding body: Cyprus Research and Innovation Foundation\u200b\u200b Funding Scheme: Restart Research 2016-2020 Programme: Proof of Concept for Technology \/ Knowhow Applications Funding Scheme: Restart Research 2016-2020 Project Title: 3D CHARACTERISATION OF THE NANOMECHANICAL PROPERTIES OF BIOLOGICALSAMPLES Acronym: 3D NANOBIOSAMPLES Duration:\u00a0 16\/5\/22-15\/2\/23 Budget:\u00a0 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"no-sidebar","site-content-layout":"page-builder","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-405","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/bionanotec.eu\/index.php\/wp-json\/wp\/v2\/pages\/405","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bionanotec.eu\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/bionanotec.eu\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/bionanotec.eu\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bionanotec.eu\/index.php\/wp-json\/wp\/v2\/comments?post=405"}],"version-history":[{"count":87,"href":"https:\/\/bionanotec.eu\/index.php\/wp-json\/wp\/v2\/pages\/405\/revisions"}],"predecessor-version":[{"id":690,"href":"https:\/\/bionanotec.eu\/index.php\/wp-json\/wp\/v2\/pages\/405\/revisions\/690"}],"wp:attachment":[{"href":"https:\/\/bionanotec.eu\/index.php\/wp-json\/wp\/v2\/media?parent=405"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}